Hypokalemic paralysis with rhabdomyolysis and arterial hypertension caused by liquorice ingestion

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Severe hypokalaemic paralysis and rhabdomyolysis due to ingestion of liquorice.

Chronic ingestion of liquorice induces a syndrome with findings similar to those in primary hyperaldosteronism. We describe a patient who, with a plasma K+ of 1.8 mmol/l, showed a paralysis and severe rhabdomyolysis after the habitual consumption of natural liquorice. Liquorice has become widely available as a flavouring agent in foods and drugs. It is important for physicians to keep liquorice...

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Rhabdomyolysis following severe hypokalemia caused by familial hypokalemic periodic paralysis

Rhabdomyolysis continues to appear with increasing frequency and represents a medical emergency requiring rapid appropriate treatment. One of the unusual causes of nontraumatic rhabdomyolysis is hypokalemic periodic paralysis without secondary causes. Primary hypokalemic periodic paralysis is a rare genetic disease characterized by episodic attacks of muscle weakness due to decreases in serum p...

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[Secondary hypokalemic paralysis in adult with hypertension].

Hypokalemic paralysis (HP) is a very uncommon condition. Few publications are available on the subject, and these are mainly case reports or small series. A patient with HP who experienced a complete recovery is reported. A 62-year-old male Caucasian patient attended the emergency room for progressive strength loss. His clinical history included morbid obesity, high blood pressure (HBP), and dy...

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Severe hypokalaemia with paralysis induced by small doses of liquorice.

A patient, who presented with a flaccid quadriplegia due to profound hypokalaemia, is described. Hypokalaemia and myoglobinuria were caused by the ingestion of small amounts of liquorice contained in a laxative preparation. Subsequent controlled administration of small amounts of this preparation induced marked hypokalaemia. This was associated with sodium retention and potassium loss confirmin...

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Low-dose liquorice ingestion resulting in severe hypokalaemic paraparesis, rhabdomyolysis and nephrogenic diabetes insipidus

In daily practice hypokalaemia is frequently observed. It can be accompanied by various adverse events and can even be life threatening. Frequent causes are intestinal and urinary loss, i.e. diarrhoea or use of diuretics. Glycyrrhizin-containing substances, such as liquorice, are a well-known but rare cause of hypokalaemia. They can induce an apparent mineralocorticoid excess-like syndrome, oft...

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ژورنال

عنوان ژورنال: Clinical Research in Cardiology

سال: 2008

ISSN: 1861-0684,1861-0692

DOI: 10.1007/s00392-008-0724-z